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carinii infection must be carefully considered in a differential diagnosis for previously healthy homosexual males with dyspnea and pneumonia.” This report was one of the early signals that revealed the AIDS epidemic.
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Although the role of CMV infection in the pathogenesis of pneumocystosis remains unknown, the possibility of P. Indeed, as mentioned in the story, one prominent example of how important MMWR has been was this June 1981 MMWR report describing five cases of Pneumocystis carinii pneumonia in five young homosexual men in Los Angeles that concluded that the “above observations suggest the possibility of a cellular-immune dysfunction related to a common exposure that predisposes individuals to opportunistic infections such as pneumocystosis and candidiasis. It described efforts by officials in the Department of Health and Human Services (HHS) to water down a Morbidity and Mortality Weekly Reports (MMWR), the weekly publication of the CDC that has served as a science-based source for the agency to inform health care professionals, scientists, and the public about health topics ranging from vaccines to infectious disease to just about everything. My impression that the FDA and CDC have been co-opted by the Trump administration is one that’s been growing for a long time, ever since Trump’s inauguration, in fact, but the story that tweaked me to write this post appeared in Politico a week ago. I fear that the list of topics on which the CDC and FDA can no longer be trusted will only grow if Donald Trump is reelected and that, even if he isn’t, some of the changes weakening the firewall between political appointees and the career scientific personnel of these agencies might be permanent and difficult for a President Biden to reverse. Now that we’re at about the six month anniversary of the first lockdowns to combat the COVID-19 pandemic, I saw a story over the weekend that led me, at the risk of being too “political,” to ask a very disturbing (to me) question: Can we still trust the CDC and FDA (and other federal agencies, like the NIH, ostensibly dedicated to upholding policy based on good science)? Although the answer is still yes for most topics, for COVID-19 increasingly the answer is no.